RDI Group

1-MM RESOLUTION SINGLE-PHOTON SPECTRAL IMAGING OF THE BRAIN

08/18/2023 - 08/18/2025

NIH/NIBIB (BRAIN Initiative), UG3 EB034715

P.I. L.J. Meng

Project description: We seek to develop an advanced brain SPECT system that offers a unique hyperspectral imaging capability substantiated by an excellent energy resolution across a wide energy range (25-600 keV), and at the same time deliver a 1- mm spatial resolution and a very high sensitivity to allow detailed visualization of multi-tracer uptakes in various brain regions.

HIGH ENERGY AND SPATIAL RESOLUTION MULTI-ISOTOPE SPECT IMAGING OF TARGETED ALPHA-EMITTERS AND THEIR DAUGHTERS

09/01/2021 - 05/31/2026

NIH/NIBIB, U01 EB031798

P.I. L.J. Meng

HYPERSPECTRAL SINGLE PHOTON IMAGING

04/01/2021 - 03/31/2026

NIH/NIBIB, R01 EB031023

P.I. L.J. Meng

SPECT IMAGING OF PERIPHERAL VASCULAR DISEASE

09/01/2019-08/31/2023

NIH/NIBIB, R01 HL145786

P.I. L.J. Meng

Project description: The goal of this project is to develop the Dynamic Extremity SPECT (DE-SPECT) system that utilizes 3-D CZT detector technology and a synthetic compound-eye camera design for dynamic and multi-tracer SPECT imaging of peripheral vascular disease (PVD) in lower extremities.

BROADBAND X-RAY FLUORESCENCE EMISSION TOMOGRAPHY

08/01/2018-04/30/2022

NIH/NIBIB, 5 R01 EB026300-03

P.I. L.J. Meng

Project description: The goal of this project is to develop an ultrahigh sensitivity, broadband X-ray fluorescence emission tomography (XFET) system. This system combines advanced CdTe X-ray imaging spectrometers assembled in a customized SPECT-like detection system design, and optimized source/filtering configurations to achieve a dramatically improved sensitivity to a broad range of metal elements that emit fluorescence x-rays of 5-100 keV.

An MR-Compatible Small Animal SPECT Based on Artificial Compound Eye Cameras (25 percentile in the 1’st review)

01/01/2017-12/31/2021

NIH/NIBIB, 1 R01 EB022388-01

P.I. L.J. Meng

Project description: The objective of this project is to develop the second generation MRC-SPECT system based on a novel artificial compound-eye gamma camera design.

Development of a Benchtop X-Ray Fluorescence Tomography System Using a Novel Geometry

05/01/2014-04/30/2018

NIBIB

P.I. L.J. Meng

Project description: The objective of this project is to develop a novel XFCT imaging system based on the use of emission tomography geometry.

An Ultrahigh Resolution MRI-compatible SPECT system

09/16/2011-09/15/2016

NIBIB, R01EB011640

P.I. L.J. Meng

Project description: The objective of this project is to develop a high resolution SPECT system to be integrated with a high-field 9.4 T MRI scanner.

Superhigh Sensitivity SPECT Imaging with Dense Camera Arrays

04/01/2014-03/31/2016

NIBIB, 1R21EB018001-01

P.I. L.J. Meng

Project description: This project is to develop an ultrahigh sensitivity SPECT system based on a novel compound-eye gamma camera design.

X-Ray Fluorescence Computer Tomography with Emission Tomography Apertures

09/15/2010-09/14/2012

NIBIB, 1R21EB009450-01A1

P.I. L.J. Meng

Project description: This project is to explore the use of emission tomography system for 3-D mapping of elemental distribution in volumetric samples.

Procurement of a Pulse Neutron Source

09/01/2010-08/31/2012

NRC, Research and Educational Infrastructure Award

P.I.: Brent Heuser, Co-P.I. L.J. Meng

Project description: For establishing a pulsed fast neutron source facility for material characterization and non-destructive testing.

Optimization of CZT Detectors with Sub-mm Pixel Pitches

03/01/2010-02430/2014

NASA, 08-APRA08-0122

P.I. of UI Subaward: L.J. Meng

Project description: We carried out a series of studies to optimize the design and fabrication techniques for highly pixelated CZT detector that would be used in hard x-ray telescopes.

A CZT Detector for MRI-Compatible SPECT Systems

09/15/2009-09/14/2011

DOE, DE-SC0001826

P.I. L.J. Meng

Project description: This project is to develop a high resolution CZT detector for future MRI-compatible SPECT systems. In this effort, we will develop two prototype detectors and associated readout electronics.

An Ultrahigh Resolution PET Detector

09/01/2008-08/31/2011

DOE, DE FG02-08ER64681

P.I. L.J. Meng

Project description: This project is to develop an ultrahigh resolution gamma ray sensor for positron emission tomography (PET) applications. The UI group is focused on the development of the readout electronics and the CZT detectors for used in the proposed PET system.

Title: A PET/SPECT/MRI System

09/01/2008-08/31/2011

NSF, Major Research Instrumentation

P.I.Steve Boppart, Co-P.I. L.J. Meng

Project description: For procurement of a Siemens Inveon PET/SPECT/CT tri-modality imaging system for molecular imaging.

An Ultrahigh Resolution MRI-compatible SPECT system

06/01/2008-05/31/2011

NCI, 1R21 CA135736-01A1

P.I. L.J. Meng

Project description: The major goal of this project is to develop a very high resolution SPECT system that can be installed inside a 4.7T MRI scanner for simultaneous SPECT/MRI image acquisition.

A Prototype SPECT/CT system for In Vivo Tracking of Radiolabeled T Cells in Mouse Brain

04/01/2008-03/31/2009

UI Research Borad

P.I. L.J. Meng

Project description: The project was focused on developing a prototype SPECT/CT device for high resolution imaging of radiolabeled T cells in living mouse.

A Very High Spatial Resolution SPECT/CT System

09/01/2004-08/31/2009

NIBIB, R21/R33 EB004940

P.I. L.J. Meng

Project description: The major goal of this project is to develop a very high resolution SPECT/CT system for 125-I imaging in small animals