JOURNAL PAPERS & PATENTS

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Conference Presentations

 

2023

  • • E. M. Zannoni, Y. Jin, P. Sankar, D. Gura, R. Wu, F. Zhang, M. Streicher, H. Yang, Z. He, S. D. Metzler, C. Liu, A. J. Sinusas, L.J. Meng, "The DE-SPECT System: A Hyperspectral SPECT System for in Vivo 3-D Gamma-Ray Spectrometry of Molecular Theranostics". 2023 IEEE NSS/MIC/RTSD Conference, Nov 2023
  • • C. Yang, E. M. Zannoni, L. Cai, M. D. Wilson, R. Bastiaannet, Y. Du, G. Sgouros, E. Frey, L.J. Meng, "Alpha-SPECT-mini: A Preclinical SPECT system Using Ultrahigh Energy Resolution CdTe detectors for Low-Dose Alpha Emitter Radiopharmaceutical Therapy Imaging". 2023 IEEE NSS/MIC/RTSD Conference, Nov 2023
  • • S. Mandot, E. M. Zannoni, M. D. Wilson, L.J. Meng, "Exploration of X-ray Fluorescence Emission Tomography for Imaging Micro-Scintillators used in Remote Optogenetics Application". 2023 IEEE NSS/MIC/RTSD Conference, Nov 2023
  • • Y. Jin, E. M. Zannoni, L.J. Meng, "Experimental Evaluation of Maximum-Likelihood-Based Data Preconditioning for DE-SPECT: A Clinical SPECT System Constructed with CZT Imaging Detectors". 2023 IEEE NSS/MIC/RTSD Conference, Nov 2023
  • • S. Mandot, E. M. Zannoni, P. La Rivière, L.-J. Meng, "X-ray Fluorescence Emission Tomography of Implantable Scintillating Microparticles for X-Ray induced Optogenetic Application", presented at the 2023 SNMMI Annual Meeting, June 2023
  • • C.Yang, E. M. Zannoni, Y.Du, , L.Cai, G. Sgouros, E. Frey, L.-J. Meng, "An Ultrahigh Energy Resolution SPECT System for Quantitative Preclinical Imaging of Targeted Alpha Therapy", presented at the 2023 SNMMI Annual Meeting, June 2023
  • • E. M. Zannoni, Y. Jin, S. Poopalasingam, S. D. Metzler, C. Liu, A. J. Sinusas, L.-J. Meng, "In Vivo 3-D Gamma-Ray Spectrometry for Multifunctional Molecular Imaging and Theragnostic in Lower Extremities", presented at the 2023 SNMMI Annual Meeting, June 2023
  • • L.-J. Meng, "Towards In Vivo 3-D Dosimetry for Alpha-Radiopharmaceutical Therapy (alpha-RPT)", Invited Talk at 2023 SORMA XIX, May 2023
  • • E. M. Zannoni, Y. Jin, S. Poopalasingam, F. Zhang, M. Streicher, H. Yang, Z. He, S. D. Metzler, C. Liu, A. J. Sinusas, L.-J. Meng, "Development of the DE-SPECT System: A hyperspectral SPECT System for in Vivo 3-D Gamma-Ray Spectrometry of Molecular Theranostics", 2023 SORMA XIX, May 2023
  • • C.Yang, E. M. Zannoni, L.Cai, M.D.Wilson, R.Bastiaannet, Y.Du, G. Sgouros, E. Frey, L.-J. Meng, "A Small-Animal SPECT System for Alpha-Emitter Radiopharmaceutical Therapy Using Hyperspectral Photon Sensors", 2023 SORMA XIX, May 2023
  • • Y.Jin, L.-J. Meng, "Spectral Temporal Double Coincidence Enhanced (STDC) SPECT", 2023 SORMA XIX, May 2023

2022

  • • E. M. Zannoni, S. Poopalasingam, Y. Jin, F. Zhang, M. Streicher, H. Yang, Z. He, S. D. Metzler, C. Liu, A. J. Sinusas, L.-J. Meng, "Development of the DE-SPECT System: A hyperspectral SPECT System for Dynamic Broadband Imaging of Peripheral Vascular Diseases ", presented at the 2022 IEEE NSS/MIC/RTSD Conference, November 2022
  • • L. Cai, E. M. Zannoni, L.-J. Meng, "In Vivo Hyperspectral Single Photon Microscopy of Targeted Alpha Therapy", presented at the 2022 IEEE NSS/MIC/RTSD Conference, November 2022
  • • S. Mandot, L. Cai, E. M. Zannoni, L.-J. Meng, "X-ray Fluorescence Emission Tomography of Implantable Micro-Scintillators for X-ray-induced Optogenetic Applications", presented at the 2022 IEEE NSS/MIC/RTSD Conference, November 2022
  • • S. D. Metzler, E. M. Zannoni, P. Sankar, C. Liu, A. J. Sinusas, L.-J. Meng, "The Impact of Additional Sampling on Hot-Spot Contrast for DE-SPECT", presented at the 2022 IEEE NSS/MIC/RTSD Conference, November 2022
  • • Y. Jin, E. M. Zannoni, L.-J. Meng, "Compton Scattering Enhanced Pinhole Imaging with the DE-SPECT - A Clinical SPECT System Constructed with CZT Imaging Spectrometers" , presented at the 2022 IEEE NSS/MIC/RTSD Conference, November 2022
  • • C. Yang, E. M. Zannoni, L.-J. Meng, "X-Y-Z-E 4-D Reconstruction of Charge Sharing Events in Small-Pixel CdTe and CZT Detectors Using Vector-Net and Joint-Net for Multi-Isotope Hyperspectral SPECT Imaging", presented at the 2022 IEEE NSS/MIC/RTSD Conference, November 2022
  • • Y. Jin, L.-J. Meng, "Imaging of Low-Activity Therapeutic Radionuclides through Time-Energy Double Coincidence (TEDC) Detection" , presented at the 2022 IEEE NSS/MIC/RTSD Conference, November 2022
  • • C. Yang, L. Pan, V. Klepov, M. G. Kanatzidis, L.-J. Meng, "Machine Learning based Waveform Analysis for CsPbBr3 Perovskite Detector to Enhance Spectral Resolution", presented at the 2022 IEEE NSS/MIC/RTSD Conference, November 2022
  • • E. M. Zannoni, S. Poopalasingam, Y.Jin, S. D. Metzler, C. Liu, A. J. Sinusas, L. J. Meng, "The DE-SPECT System: The First Clinical SPECT System for Broadband Multi-Isotope Imaging of the Lower Extremities", presented at the 2022 SNMMI Annual Meeting, June 2022
  • • L. Cai, E.M. Zannoni, L.J. Meng, "An Ultrahigh Energy Resolution SPECT System for Hyperspectral and Quantitative Imaging in Targeted Alpha Therapy", presented at the 2022 SNMMI Annual Meeting, June 2022
  • • C. Yang, E. M. Zannoni, L. J. Meng, "Machine-Learning Based Energy Correction Technique for use in Dedicated Pre-Clinical and Clinical SPECT Imaging of Targeted Alpha Therapy", presented at the 2022 SNMMI Annual Meeting, June 2022
  • • S. Mandot, E.M. Zannoni, L.Cai, X. Nie, L.J. Meng, , "Performance evaluation of a Full-ring X-ray Fluorescence Emission Tomography System equipped with multi-slit and multi-pinhole collimators", presented at the 2022 SNMMI Annual Meeting, June 2022
  • • S. Poopalasingam, E. M. Zannoni, C. Liu, A. J. Sinusas, L. J. Meng, S. D. Metzler, "Evaluation of DE-SPECT Pinholes Exchange Adaptive Mechanism", presented at the 2022 SNMMI Annual Meeting, June 2022

2021

  • • E. M. Zannoni, S. Poopalasingam, S. D. Metzler, C. Liu, A. J. Sinusas, L. J. Meng, "The DE-SPECT System: A Clinical SPECT System based on 1-cm Thick CZT Imaging Spectrometers and Dynamic Compound-Eye Collimators for Broadband Multi-Isotope Imaging of the Lower Extremities", presented at the 2021 Virtual IEEE NSS/MIC/RTSD Conference, Oct 2021
  • • E. M. Zannoni, Can Yang, Thomas X. Wei, Deana C. McDonagh, Ling Jian Meng, "Design Study of a Brain SPECT System based on Synthetic Compound-Eye Camera Design and Micro-Ring Apertures for Ultrahigh Resolution Brain Imaging", presented at the 2021 Virtual IEEE NSS/MIC/RTSD Conference, Oct 2021
  • • C. Yang, E. M. Zannoni, L. - J. Meng, "Joint Estimation of Interaction Position and Energy Deposition in Ultrahigh Resolution CZT and CdTe Imaging Sensors using Machine Learning and Its Application in Multi-Isotope Hyperspectral SPECT Imaging", presented at the 2021 Virtual IEEE NSS/MIC/RTSD Conference, Oct 2021
  • • X. Nie, A. V. Avachat, E. M. Zannoni, L. Cai, M. Anastasio, P. L. Riviere, L. Meng, "A Benchtop High-Sensitivity X-ray Fluorescence Emission Tomography (XFET) System Comprising Full Ring CdTe Spectrometers and Liquid-metal-jet-based X-ray Source", presented at the 2021 Virtual IEEE NSS/MIC/RTSD Conference, Oct 2021
  • • L. Cai, E. M. Zannoni, X. Nie, L. - J. Meng, "Multi-Isotope Imaging of Therapeutic Alpha Emitters and Their Daughters with an Ultrahigh Energy Resolution Spectral SPECT Imaging System", presented at the 2021 Virtual IEEE NSS/MIC/RTSD Conference, Oct 2021
  • • Y. Jin, P. Tanton, M. Streicher, H. Yang, S. Brown, Z. He, L. - J. Meng,"Compton-Enhanced PET Imaging with High-Resolution 3-D CZT Imaging Detectors", presented at the 2021 Virtual IEEE NSS/MIC/RTSD Conference, Oct 2021
  • • E.M. Zannoni, C.Yang, L.-J. Meng , “Design study of a high-resolution and ultrahigh-sensitivity brain SPECT system for imaging medically intractable epilepsy”, J Nucl Med, May 1, 2021, vol. 62, no. supplement 1, 39, presented at SNMMI 2021 Virtual Annual Meeting, June 2021
  • • E.M. Zannoni, P. Sankar, S. Metzler, C. Liu, A. Sinusas, L.-J. Meng , “Design and development of the DE-SPECT system: A clinical SPECT system dedicated for dynamic imaging of peripheral vascular diseases”, J Nucl Med, May 1, 2021, vol. 62, no. supplement 1, 1143, presented at SNMMI 2021 Virtual Annual Meeting, June 2021
  • • L. Cai, E. M. Zannoni, X. Nie, L.-J. Meng, “Hyperspectral Single Photon Imaging of Targeted Alpha Therapy”, J Nucl Med, May 1, 2021, vol. 62, no. supplement 1, 1141, presented at SNMMI 2021 Virtual Annual Meeting, June 2021
  • • Y. Jin, P. Tanton, M. Streicher, H. Yang, S. Brown, Z. He and L.-J. Meng, “Experimental evaluation of a prototype combined PET-Compton imaging system based on 3-D position-sensitive CZT detectors for dedicated breast cancer imaging”, J Nucl Med, May 1, 2021, vol. 62, no. supplement 1, 1129, presented at SNMMI 2021 Virtual Annual Meeting, June 2021

2020

  • • Y. Jin, M. Streicher, H. Yang, S. Brown, Z. He, L. - J. Meng, “Experimental Evaluation of An Ultrahigh Resolution Small Animal PET Scanner Based on 3-D Position-Sensitive CZT Detectors”, IEEE NSS/MIC Conference, Virtual, Boston (USA), November 2020
  • • C. Yang, E. M. Zannoni, L. - J. Meng, “Design Study of the I-SPECT System: An Intraoperative SPECT System Using a Deformable Dense Camera Array (DCA) and High-resolution Imaging Spectrometers”, IEEE NSS/MIC Conference, Virtual, Boston (USA), November 2020
  • • E. M. Zannoni, M. D. Wilson, L. - J. Meng, “The MRC-SPECT-II System: A MR-Compatible Small-Animal SPECT System Based on Imaging Spectrometer and Inverted Compound-Eye Gamma Camera Design”, IEEE NSS/MIC Conference, Virtual, Boston (USA), November 2020
  • • L. - J. Meng, P. Tanton, Y. Jin, S. Brown, H. Yang, M. Streicher, Z. He, “Near-Field Compton Imaging of Alpha-Emitter Radiopharmaceutical Therapeutics ( a-RPT) Using Large Volume CZT Detectors”, IEEE NSS/MIC Conference, Virtual, Boston (USA), November 2020
  • • X. Nie, Y. Chen, E. M. Zannoni, L. - J. Meng, “A High-Sensitivity Full-Ring X-ray Fluorescence Emission Tomography System for In Vivo Imaging of Non-Radioactive Metal-based Therapeutic Agents in Small Animals”, IEEE NSS/MIC Conference, Virtual, Boston (USA), November 2020

2019

  • • Y. Chen, X. Nie, Y. Lu, P. L. Riviere, L. - J. Meng, “A Benchtop X-ray Fluorescence Emission Tomography System for Mapping Copper, Iron, and Zinc in Alzheimer’s Disease Mouse Brain Tissues”, IEEE NSS/MIC Conference, Manchester, UK, November 2019
  • • X. Nie, Y. Chen, L. Meng, “Label-Free Molecular Imaging using a Polarized X-ray Fluorescence Computed Tomography System with Multi-Leaf Compton Mirror”, IEEE NSS/MIC Conference, Manchester, UK, November 2019
  • • J. Zhang, E. M. Zannoni, E. Frey, Y. Du, L. - J. Meng, “Hyperspectral single photon imaging of targeted alpha therapy: development of the alpha-SPECT system based on advanced CZT imaging spectrometers ”, IEEE NSS/MIC Conference, Manchester, UK, November 2019
  • • L. - J. Meng, J. Zhang, E.M. Zannoni, M. Wilson, K. Iniewski, “Development of Large-Area Deformable HEXITEC-CZT Imaging-Spectrometer for Clinical SPECT Imaging Applications”, IEEE NSS/MIC Conference, Manchester, UK, November 2019
  • • E. M. Zannoni, J. Zhang, L.-J. Meng, “The MRC-SPECT-II System: Preliminary performance evaluation of the second-generation MR-compatible SPECT system”, IEEE NSS/MIC Conference, Manchester, UK, November 2019
  • •Yunlai Chen, Xingchen Nie, Elena Maria Zannoni and Ling-jian Meng, “A Partial ring X-ray Fluorescence Computed Tomography Imaging Platform for In Vivo Imaging of Non-Radioactive Metal-based Therapeutic Agents in Small Animals”, J Nucl Med, May 1, 2019, vol. 60, no. supplement 1, 318, Presented at SNMMI Annual Meeting in Anaheim, CA, USA, June 2019
  • •Xingchen Nie, Yunlai Chen and Ling-Jian Meng, “Towards Zero Compton Background in X-ray Fluorescence Computed Tomography (XFCT)”, J Nucl Med, May 1, 2019, vol. 60, no. supplement 1, 1352, Presented at SNMMI Annual Meeting in Anaheim, CA, USA, June 2019
  • •Elena Maria Zannoni and Ling-Jian Meng , “Intraoperative C-arm SPECT for hybrid operating room: A design study”, J Nucl Med, May 1, 2019, vol. 60, no. supplement 1, 316, Presented at SNMMI Annual Meeting in Anaheim, CA, USA, June 2019
  • •Jiajin Zhang, Elena Maria Zannoni, Yong Du, Eric Frey and Ling-Jian Meng , “Alpha-SPECT: Hyperspectral single photon imaging of targeted a-emission therapy”, J Nucl Med, May 1, 2019, vol. 60, no. supplement 1, 311, Presented at SNMMI Annual Meeting in Anaheim, CA, USA, June 2019

2018

  • • E. M. Zannoni, J. Zhang, M. D. Wilson, L.-J. Meng,“Development of the MRC-SPECT-II System: A Simultaneous SPECT-MR system based on Inverted Compound Gamma Camera”, IEEE NSS/MIC Conference, Sydney, AUS, November 2018
  • • E. M. Zannoni, L.-J. Meng, “Design Study for the DC-SPECT System: An Ultrahigh-Sensitivity Dynamic Cardiac Imaging System with Compound Eye Gamma Camera and Micro-Slit Apertures”, IEEE NSS/MIC Conference, Sydney, AUS, November 2018
  • • Y. Chen, J. George, E. M. Zannoni, L. - J. Meng, “A High-Sensitivity Desktop X-ray Fluorescence Emission Tomography System towards In Vivo Imaging of Trace Metals in Small Animals”, IEEE NSS/MIC Conference, Sydney, AUS, November 2018
  • • J. George, Y. Chen, L. - J. Meng, “Benchtop X-ray Fluorescence Computed Tomography of Heavy Metal Nanoparticles”, IEEE NSS/MIC Conference, Sydney, AUS, November 2018
  • • Z. Liu, J. George, L. - J. Meng, “Nondestructive Assessment of Transportation Fuel Cask using Time-Tagged Neutron Interrogations”, IEEE NSS/MIC Conference, Sydney, AUS, November 2018
  • • Jiajin Zhang, Xingchen Nie, Jianyong Jiang, Sergey Komarov, Yuan-chuan Tai1 and Ling-Jian Meng, “Hybrid Scintillator-Semiconductor Detector (HSSD) for Ultrahigh Resolution PET Imaging”, J Nucl Med, May 1, 2018, vol. 59, no. supplement 1, 1230, Presented at SNMMI Annual Meeting in Philadelphia, PA, USA, June 2018
  • •Jiajin Zhang, Elena Maria Zannoni, Matthew Wilson and Ling-Jian Meng, “Development of 3D HEXITEC CdZnTe detector - A large area high-resolution ?-ray imaging camera for future SPECT imaging”, J Nucl Med, May 1, 2018, vol. 59, no. supplement 1, 1770a, Presented at SNMMI Annual Meeting in Philadelphia, PA, USA, June 2018
  • •Elena Maria Zannoni, Jiajin Zhang, Chao Ma, Jinsong Ouyang, Scott Metzler and Ling-Jian Meng, “Design study for MRC-SPECT-C: A MR-compatible cardiac SPECT system for simultaneous SPECT/MR cardiac imaging”, J Nucl Med, May 1, 2018, vol. 59, no. supplement 1, 357, Presented at SNMMI Annual Meeting in Philadelphia, PA, USA, June 2018
  • • Elena Maria Zannoni, Jiajin Zhang and Ling-Jian Meng, “Hyperspectral SPECT: Time to revisit the spectral domain for gamma ray imaging?”, J Nucl Med, May 1, 2018, vol. 59, no. supplement 1, 361, Presented at SNMMI Annual Meeting in Philadelphia, PA, USA, June 2018
  • •Yunlai Chen, Jonathan George, Elena Maria Zannoni and Ling-Jian Meng, “A Multi-Contrast X-ray Fluorescence, X-ray Luminescence and X-ray CT Functional Imaging Platform for In Vivo Imaging of Non-Radioactive Therapeutic Agents in Small Animals”, J Nucl Med, May 1, 2018, vol. 59, no. supplement 1, 1760, Presented at SNMMI Annual Meeting in Philadelphia, PA, USA, June 2018
  • •Jonathan George, Yunlai Chen, Anil Kumar, Wen Jiang, Jin Xie and Ling-Jian Meng, “Real-time Dosimetry Imaging of Nanoparticle-Mediated Radiation Therapy with Integrated X-ray Luminescence and X-ray Fluorescence Imaging”, J Nucl Med, May 1, 2018, vol. 59, no. supplement 1, 364, Presented at SNMMI Annual Meeting in Philadelphia, PA, USA, June 2018

2017

  • • E. M. Zannoni, X. Lai, M. D. Wilson, L.-J. Meng,“Experimental Design Study for MRC-SPECT-II System: A Hyperspectral Simultaneous SPECT-MR system based on Inverted Compound Gamma Camera”, IEEE NSS/MIC Conference, Atlanta, USA, November 2017
  • • E. M. Zannoni, L. Zhou, Y. Zhang, L.-J. Meng, “Simultaneous MR-Guided Adaptive SPECT System based on Soft Robotics: An Experimental Feasibility Study”, IEEE NSS/MIC Conference, Atlanta, USA, November 2017
  • • E. M. Zannoni, J.George, L. Yin, J. Zhang, P. Seller, M. C. Veale, M. D. Wilson, L.J. Meng, “Broadband X-ray Fluorescence Emission Tomography”, IEEE NSS/MIC Conference, Atlanta, USA, November 2017
  • • L.-J. Meng, E. M. Zannoni, X. Lai, M. D. Wilson, “From MRC-SPECT-I to MRC-SPECT-II: Towards High-Performance MR-Compatible SPECT Imaging of Small Lab Animals”, Dedicated Brain Imaging Systems Workshop, IEEE NSS/MIC Conference, Atlanta, USA, November 2017
  • • J. George, E. M. Zannoni, M. Wilson, L.-J. Meng, “Broadband X-ray Fluorescence Emission Tomography”, Non-Conventional Emission Tomography Techniques and Their Applications in Image- Guided Therapeutics Workshop, IEEE NSS/MIC Conference, Atlanta, USA, November 2017
  • • A. Groll, L.J. Meng, "Comparative Performance Analysis of Scintillation and Semiconductor Imaging Systems: Progression Toward a High Resolution Preclinical Semiconductor-Based PET Modality", IEEE NSS/MIC Conference, Atlanta, USA, November 2017
  • • J. George, L.J. Meng,“Energy-Matching X-ray Fluorescence Computed Tomography: An Evaluation of the Effects of Incident Beam Energy on Imaging Performance of Nanoparticles”, IEEE NSS/MIC Conference, Atlanta, USA, November 2017
  • • J. George, B. Quigley, P. La Riviere, L.J. Meng,“An Evaluation of a Quad-Modality X-ray Luminescence, Fluorescence, Scattering and Transmission Computed Tomography System for Monitoring Nanoparticle-Mediated Therapies”, IEEE NSS/MIC Conference, Atlanta, USA, November 2017
  • • S. Metzler and L-J Meng, “Collimator Design for a Dedicated Human Cardiac SPECT System with High Resolution Detectors”, J Nucl Med, May 1, 2017, vol. 58, no. supplement 1, 58:29, Presented at SNMMI Annual Meeting in Denver, CO, USA, June 2017
  • • A. Groll, K. Kim, Q. Li, and L-J Meng, “Ultrahigh Resolution Coplanar PET Imaging of Microfluidic Devices for Synthesizing PET Radiopharmaceuticals”, J Nucl Med, May 1, 2017, vol. 58, no. supplement 1, 58:90, Presented at SNMMI Annual Meeting in Denver, CO, USA, June 2017
  • • J. George, B. H. Yoon, and L-J. Meng, “A Quad-Modality X-ray Luminescence, X-ray Fluorescence, X-ray Rayleigh Scattering and X-ray Transmission Computed Tomography Imaging Platform for Monitoring and Stimulating the Therapeutic Delivery of Metal-Containing Nanoparticles”, J Nucl Med, May 1, 2017, vol. 58, no. supplement 1, 58:151, Presented at SNMMI Annual Meeting in Denver, CO, USA, June 2017
  • • X.Lai, L-J. Meng, “Development of the MRC-SPECT-II System:Experimental Evaluation and Modeling of a Prototype Inverted-Compound-Eye Gamma Camera”, J Nucl Med, May 1, 2017, vol. 58, no. supplement 1, 58:225, Presented at SNMMI Annual Meeting in Denver, CO, USA, June 2017
  • • E.M. Zannoni, J.George, P. Seller, M. C. Veale, M. D. Wilson, M. Li L-J. Meng, “Broadband X-ray Fluorescence Emission Tomography with A Small Pixel CdTe Imaging-Spectrometry Detector”, J Nucl Med, May 1, 2017, vol. 58, no. supplement 1, 58:401, Presented at SNMMI Annual Meeting in Denver, CO, USA, June 2017
  • • E.M. Zannoni, X. Lai, L-J Meng, “Design study for MRC-SPECT-II: The second generation MRI compatible SPECT system based on hyperspectral compound-eye gamma cameras”, J Nucl Med, May 1, 2017, vol. 58, no. supplement 1, 58:1321, Presented at SNMMI Annual Meeting in Denver, CO, USA, June 2017
  • • E. M. Zannoni, X. Lai, P. Seller, M. C. Veale, M. D. Wilson, and L.J. Meng, “Development of MRC-SPECT-II: The Second-Generation MR-Compatible SPECT System for Hyperspectral MR/SPECT Imaging” PSMR Conference, Lisbon, Portugal, May 2017

2016

  • • E.M. Zannoni, X. Lai, L-J Meng, “Design Study for MRC-SPECT-II: A new generation of MR-Compatible SPECT System bioinspired by superposition compound eyes for ultrahigh resolution SPECT Imaging”, J Nucl Med, May 1, 2016, vol. 57, no. supplement 2, 57:91, Presented at SNMMI Annual Meeting in San Diego, CA, USA, June 2016
  • • X.Lai, B.Odintsov, I.V. Balyasnikova, L.Cai, E.M. Zannoni, D.Yu, S-H. Cheng, C-T. Chen, L-J. Meng, “Imaging Studies of An Ultrahigh Resolution Simultaneous SPECT/MRI System for imaging Neural Stem Cell in a Mouse Brain”, J Nucl Med, May 1, 2016, vol. 57, no. supplement 2, 57:106, Presented at SNMMI Annual Meeting in San Diego, CA, USA, June 2016
  • • L. Giannoni, J. George, X. Lai, and LJ Meng, “Design and Feasibility Study of a Full-Ring X-ray Fluorescence Emission Computed Tomography System based on Small-Pixel CdTe Detectors for Real-Time Monitoring of X-ray Induced and Nanoparticle Mediated Radiation Therapy” , SNMMI Annual Meeting in San Diego, CA, USA, June 2016
  • • J. George, L. Giannoni, K. Kim, J. Dutta, Q. Li, P.J. La Riviere, and LJ Meng, “Hybrid X-ray Fluorescence, Luminescence and Transmission Computed Tomography for Image-Guided Nanoparticle Mediated X-ray Micro-Beam Therapy”, SNMMI Annual Meeting in San Diego, CA, USA, June 2016
  • • A. Groll, K. Kim, J.C. Wang, J. H. Wang, Q. Li and L.J. Meng, “A Prototype Ultrahigh Resolution PET Imaging System based on Hybrid Pixel-Waveform (HPWF) CdTe Detectors: Evaluation of CdTe PET for In Vivo Investigation of Neurodegenerative Disorders in Transgenic Mouse Models”, SNMMI Annual Meeting, San Diego, CA, USA, June 2016

2015

  • • X. Lai, B.Odintsov, C. Liang, E.M. Zannoni, I. V. Balyasnikova, C-T. Chen, L-J. Meng, “First simultaneous sub-500 µm-resolution SPECT/MRI Imaging with the MRC-SPECT-I: an Ultrahigh Resolution MR-Compatible SPECT System using highly pixelated semiconductor detectors”, IEEE NSS/MIC Conference, San Diego, CA, USA, November 2015
  • • L.J Meng, X. Lai, “Synthetic Compound Eye Gamma Camera for SPECT Imaging: Systems within Systems”, IEEE NSS/MIC Conference, San Diego, CA, USA, November 2015
  • • X. Lai et al, “Experimental Evaluation of Prototype Compound Eye Camera for Use in the Second Generation of MRI Compatible SPECT Imaging”, IEEE NSS/MIC Conference, San Diego, CA, USA, November 2015
  • • A. Groll, K. Kim, J.C. Wang, J. H. Wang, Q. Li and L.J. Meng, “Hybrid Pixel-Waveform (HPWF) CdTe Detectors: Towards Sub-300 µm Resolution PET Imaging of Transgenic Mice with Neurodegenerative Disease”, IEEE NSS/MIC Conference, San Diego, CA, USA, November 2015
  • • J. George, D. Strat, B. Quigley, P.J. La Riviere, L.J. Meng, “Experimental Evaluation of a Combined X-ray Fluorescence Emission Tomography and X-ray Luminescent Computed Tomography System Towards Quantifying and Imaging Therapeutic Nanoparticles”, IEEE NSS/MIC Conference, San Diego, CA, November 2015
  • • X. Lai,et al, “MRC-SPECT-DF: An MR-Compatible SPECT System with A Dual-FOV Collimator Design for Microscopic SPECT Imaging”, SNMMI Annual Meeting, Baltimore, MD, USA, June 2015
  • • K. Kim, J. Dutta, A. Groll, G.E. Fakhri, L.J. Meng, and Q. Li, “Penalized Maximum Likelihood Reconstruction of Ultrahigh Resolution PET with Depth of Interaction”, Fully 3D Conference, Newport, RI, USA, June 2015
  • • A. Groll, K. Kim, J. Dutta, Q. Li and L.J. Meng, “Evaluation of Hybrid Pixel-Waveform (HPWF) CdTe and CZT Detectors for Sub-500 micron Resolution PET Imaging for Mouse Brain Studies”, SNMMI Annual Meeting, Baltimore, MD, USA, June 2015
  • • J. George, A. Groll, S.H. Cheng, C.T. Chen, P.J. La Riviere, J.S.Souris, L.-W. Lo, and L.J. Meng, “Evaluation of X-ray Emission Tomography for Real-time Assessment of Photodynamic Therapy Effect”, SNMMI Annual Meeting, Baltimore, MD, USA, June 2015
  • • I. V. Balyasnikova, X. Lai, et al , “Imaging of StemCell in the Brain Using Integrated High-Performance SPECT/CT and SPECT/MR Systems”, SNMMI Mid-Winter Meeting, San Antonio, TX, January 2015

2014

  • • A. Groll, and L.J. Meng, “Hybrid Pixel-Waveform (HPWF) CdTe and CZT Detectors for Sub-500 micron Resolution PET Imaging Systems”, IEEE NSS/MIC Conference, Seattle, WA, USA, November 2014
  • • A. Groll, J. George, Z. Liu, D. Strat, P.J. La Riviere, and L.J. Meng, “Stimulated Emission Tomography for Mapping and Region-of-Interest Quantification of Trace Metals in Biological Samples”, IEEE NSS/MIC Conference, Seattle, Washington, USA, November 2014
  • • X. Lai et al, “Microscopic SPECT Imaging with Inverted Compound Eye Cameras”, IEEE NSS/MIC Conference, Seattle, WA, USA, November 2014
  • • X. Lai et al, “MRC -SPECT-I: an Ultrahigh Resolution MR-Compatible SPECT System with Dual FOV Aperture”, IEEE NSS/MIC Conference, Seattle, WA, USA, November 2014
  • • L.J Meng and X. Lai, “Synthetic Sampling for Region of Interest (ROI) Imaging Using an Ultrahigh Resolution Stationary SPECT System”, IEEE NSS/MIC Conference, Seattle, WA, USA, November 2014
  • • X. Lai, et al, “Preliminary Imaging Studies of MRC-SPECT: An Ultrahigh Resolution MR-compatible Small Animal SPECT System Using Highly Pixelated CdTe Detectors”, SNMMI Annual Meeting, St.Louis, MO, USA, June 2014

2013

  • • A. Groll, J. George, P. Vargas, P.J. La Riviere, and L.J. Meng, “Element Identification in Organic Samples Utilizing a Benchtop X-ray Fluorescence Emission Tomography (XFET) System”, IEEE NSS/MIC Conference, Seoul, South Korea, November 2013
  • • X. Lai and L.J Meng, “MRC -SPECT-II: Artificial Compound-Eye Gamma Camera for SPECT Imaging”, IEEE NSS/MIC Conference, Seoul, South Korea, November 2013
  • • L.J Meng, L. Cai, X. Lai, et al, , “MRC-SPECT: An Ultrahigh MR-Compatible SPECT System Based on Small-Pixel CdTe Detectors”, IEEE NSS/MIC Conference, Seoul, South Korea, November 2013

2012

  • • X. Lai, L. Cai, L. J. Meng, “Microscopic SPECT Imaging with Micro-Ring Apertures and High Resolution Semiconductor Detector”, IEEE NSS/MIC Conference, Anaheim, CA, USA, November 2012

2011

  • • X. Lai, et al.“A Concept Design of a Compton Scattering Light Source Based on the HLS Electron Storage Ring”, Proceedings of 2011 Particle Accelerator Conference Record, New York, NY, USA

2010

  • • L. Cai, G. Fu and L. J. Meng, “A Very-High Resolution SPECT System Based on the Energy-Resolved Photon-counting(ERPC) CdTe Detectors”, IEEE NSS/MIC Conference Record, Knoxville, November 2010.
  • • J. W. Tan, L. Cai and L. J. Meng, “Experimental Study of the Response of 1-5 mm Thick CZT/CdTe Detectors inside Strong Magnetic Field”, IEEE NSS/MIC Conference Record, Knoxville, November 2010
  • • N. Li and L. J. Meng, “An Adaptive and Non-Uniform SPECT Angular Sampling Approach For Optimizing Estimation Task Performances”, IEEE NSS/MIC Conference Record, Knoxville, November 2010.
  • • Y. Yin, H. Wu, S. Komarov, A. Garson, Q. Guo, H. Krawczynski, L. J. Meng, Y.-C. Tai, “3D Spatial Resolution of 350µm Pitched Pixelated CdZnTe Detectors for PET Imaging Application”, IEEE NSS/MIC Conference Record, Knoxville, November 2010.
  • • Q. Guo, T. Michel, G. Alfred, J. Martin, M. Beilicke, K. Lee, D. Juergen, F. Bayer, G. Anton, B. Ramsey, L. J. Meng, H. Krawczynski1, “Design of a Si-CZT Hard X-Ray Imaging Polarimeter”, IEEE NSS/MIC Conference Record, Knoxville, November 2010.
  • • Y. Yin, H. Wu, S. Komarov, A. Garson, Q. Guo, H. Krawczynski, L. J. Meng, Y.-C. Tai1, Coincidence Measurement of 350µm Pitched Pixelated CdZnTe Detector with LSO PET Module”, IEEE NSS/MIC Conference Record, Knoxville, November 2010.
  • • L. J. Meng, Geng Fu, Nan Li, and Patrick La Riviere, “X-ray Fluorescence Emission Tomography (XFET) – Towards 3D Mapping of Trace-Metals in Biological Samples With A Bench-Top X-ray Source”, IEEE NSS/MIC Conference , Knoxville, November 2010.
  • • L. J. Meng, Jia-Wei Tan and Cai Liang, “Sub-500 mm Resolution SPECT Imaging Inside a 3T MRI Scanner”, IEEE NSS/MIC Conference, Knoxville, November 2010.
  • • L. J. Meng, J. W. Tan, L. Cai, Qingzhen Guo, and H. S. Krawczynski , “Development of Small-Pixel CZT and CdTe Detectors Read Out by a Novel Energy-Resolved Photon-Counting ASIC”, IEEE NSS/MIC Conference, Knoxville, November 2010.
  • • L. J. Meng; Geng Fu; Nan Li; Matt Newville; Peter Eng; Patrick La Rivière, “X-ray fluorescence tomography using imaging detectors”, Proceedings of SPIE, 2010, Vol. 7084, August 2010
  • • L. J. Meng; Geng Fu; Nan Li; Matt Newville; Peter Eng; Patrick La Rivière, “X-ray fluorescence tomography using imaging detectors”, SPIE Conference on Developments in X-Ray Tomography VII, August 2010.
  • • L. J. Meng, Jia-Wei Tan and Cai Liang, “Sub-500 mm Resolution SPECT Imaging Inside a 3T MRI Scanner”, Symposium on Radiation Measurements and Applications (SORMA), Ann Arbor, May 2010.
  • • J. W. Tan and L. J. Meng, “Comparing Ultrahigh Resolution Scintillation and Semiconductor Detectors for SPECT Imaging of Ultra-low Activity Objects”, Proceedings of 2010 Symposium on Radiation Measurements and Applications (SORMA), May 2010
  • • L. J. Meng, Geng Fu, Nan Li, Matt Newville, Peter Eng and Patrick La Riviere, “X-ray Fluorescence Emission Tomography (XFET) for Imaging Trace-Metals in Plant”, Symposium on Radiation Measurements and Applications (SORMA), Ann Arbor, May 2010.
  • • L. J. Meng, L. Cai and J. W. Tan, “Technological Development Towards Sub-500 mm Resolution SPECT Imaging Inside MR Scanners”, Fourth workshop on small animal, single photon emission computed tomography (SPECT), Tucson, Arizona, 2010

2008

  • • L. J. Meng, J. W. Tan, P. J. La Riviere and N. H. Clinthorne, “Feasibility of Synchrotron X-ray Fluorescence Computed Tomography Using An Emission Tomography System”, SORMA West 2008 Conference, Berkeley, CA, June 2008
  • • L. J. Meng, J. W. Tan, P. J. La Riviere and N. H. Clinthorne, “Feasibility of Synchrotron X-ray Fluorescence Computed Tomography Using An Emission Tomography System”, SORMA West 2008 Conference, Berkeley, CA, June 2008.
  • • L. J. Meng, G. Fu, J. W. Tan and C. T. Chen , “Development of the Gamma Cube – An Ultrahigh Resolution, High Sensitivity SPECT System for In Vivo Imaging of Radiolabeled T Cells in Mouse Brain”, SORMA West 2008 conference, Berkeley, CA, June 2008
  • • L. J. Meng, P. J. La Riviere, Geng Fu, Peter Eng and Matt Newville, “ Beam Testing of Imaging Spectrometry Detectors for Synchrotron X-ray Fluorescence Computed Tomography”, IEEE NSS/MIC Conference, Dresden, Germany, November 2008
  • • L.-J. Meng, S. Konstantinos, T. Schulman, “Preliminary Results from a Novel Energy-Resolved Photon-Counting CdTe Detector”, IEEE NSS/MIC Conference Record, 2008.
  • • Geng Fu, Ling-Jian Meng, and Chin-Tu Chen, “Design Study of Gamma Cube – An Ultrahigh Resolution, High Sensitivity SPECT System for In Vivo Mouse Brain”, IEEE NSS/MIC Conference Record, 2008.
  • • L. J. Meng, G. Fu and C. T. Chen, “An Ultrahigh Resolution SPECT System for Mouse Brain Studies”, IEEE NSS/MIC Conference Record, 2008.
  • • Jia-Wei Tan, Ling-Jian Meng , and Geng Fu, “A Prototype MRI-Compatible Ultra-High Resolution SPECT for in Vivo Mice Brain Imaging”, IEEE NSS/MIC Conference Record, 2008.
  • • Ling-Jian Meng and Nan Li, “A Vector Uniform Cramer-Rao Bound for SPECT System Design” , IEEE NSS/MIC Conference Record, 2008.
    • L. J. Meng, P. J. La Riviere, Nan Li, Geng Fu, Peter Eng, Matt Newville, “Feasibility Study of Using An Emission Tomography System for Synchrotron X-ray Fluorescence Computed Tomography” , IEEE NSS/MIC Conference Record, 2008.

2007

  • • L. J. Meng, G. Fu, J. W. Tan, C.-T. Chen, “An Ultra-High Resolution SPECT/CT System”, SNM Annual Meeting, Washington DC, June 2007.
  • • L. J. Meng, G. Fu, J. W. Tan, C. T. Chen, “Design and Preliminary Studies of a Single Photon Emission Microscope System for Mice Brain Studies”, SNM Annual Meeting, Washington DC, June 2007.
  • • L. J. Meng, “Self-adapting Aperture System for Single Photon Emission Microscope System”, SNM Annual Meeting, Washington DC, June 2007.
  • • L.J. Meng, Geng Fu, E. J. Roy, B. Saupe, Jun-Guo Bian, Chin-Tu Chen, Neal. Clinthorne, “Development of an Ultrahigh Resolution SPECT System for In Vivo Tracking of Radio-labeled T Cells in Mouse Brain”, IEEE NSS/MIC Conference , Honolulu, HI, November 2007.
  • • L.J. Meng, Jia-Wei Tan, and Geng Fu, “Design Study of an MRI Compatible Ultra-High Resolution SPECT for In Vivo Mice Brain Imaging”, IEEE NSS/MIC Conference Record, 2007.
  • • Geng Fu, Jia-wei Tan, and Ling-Jian Meng, “Aperture Design for Ultra-high Resolution SPECT Systems for Small Animal Imaging”, IEEE NSS/MIC Conference Record, 2007

2006

  • • L. J. Meng, Chien-Min Kao, Di Li, Seungryong Cho, Charles Pelizzari, Jeffrey Souris, Xiaochuan Pan, Chin-Tu Chen, “Imaging Performance of an Ultra-High Resolution SPECT/CT System”, IEEE NSS/MIC Conference Record.

2005

  • • L. J. Meng, Z. He, B. Alexander and J. Sandoval, “Spectroscopic Performance of 1 cm thick HgI2 Detectors”, IEEE NSS/MIC Conference Record, 2005.
  • • Feng Zhang, Zhong He, L.J. Meng, “Prototype PET System Using Two 3-D Position Sensitive CdZnTe Detectors”, IEEE NSS/MIC Conference Record, 2005.
  • • L. J. Meng, “Design of a Single Photon Emission Microscope for Small Animal I-125 Imaging”, SNM Annual Meeting, Toronto, Canada, June 2005.

2004

  • • L. J. Meng and Z. He, “Timing Resolution of Large Volume HgI2 Detectors”, IEEE NSS/MIC RTSD Conference, Rome, Italy, November 2004.
  • • Z. He and L. J. Meng, “Feasibility Study of 3-D CdZnTe Detectors for PET Imaging”, IEEE NSS/MIC RTSD Conference, Rome, Italy, November 2004.
  • • Keitaro Hitomi, L. J. Meng and Z. He, “Evaluation of Pixellated HgI2 Detectors”, IEEE NSS/MIC RTSD Conference, Rome, Italy, November 2004.
  • • N. H. Clinthorne, L. J. Meng, “Optimality of the Post-smoothed, penalised Maximum Likelihood Estimator for Imaging Reconstruction”, SNM Annual Meeting, Philadelphia, PA, June 2004.

2003

  • • L. J. Meng, W. L. Rogers, N. H. Clinthorne, “Aperture Design for I125 Small Animal Imaging Using A Very High Resolution Scintillation Camera”, SNM Annual Meeting, San Francisco, CA, August 2003
  • • L. J. Meng, N. H. Clinthorne, W. L. Rogers, “Aperture Design for I125 Small Animal Imaging Using A Very High Resolution Scintillation Camera”, SNM Annual Meeting, San Francisco, August 2003.
  • • L. J. Meng and D. K. Wehe, “A Gamma Ray Imager Using Clustered Non-Redundant Array Coded Aperture”, IEEE NSS/MIC Conference Record, 2003.

2002

  • • L. J. Meng, W. L. Rogers, N. Clinthorne, J. Fessler, “Feasibility Study of Compton Scattering Enhanced Multiple Pinhole Imager for Nuclear Medicine”, IEEE NSS/MIC Conference Record, 2002.
  • • L J Meng, D. K. Wehe, “A Feasibility Study of Using Combined Mechanical and Electronic Collimation for Nuclear Environment”, IEEE NSS/MIC Conference Record, 2002.

2001

  • • L. J. Meng, D. J. Herbert, and D. Ramsden, “Design and Feasibility Study of an Ultra-fast High Resolution PET Detector”, IEEE NSS/MIC Conference Record, 2001.
  • • L. J. Meng, W. Gilboy, D. Ramsden, “Measurements of Th, U and K Concentrations Using A Large Volume CsI Detector and Gamma-ray Spectroscopy”, IEEE NSS/MIC Conference Record, 2001.
  • • S. M. Ignatov V. M. Chirkin, V. N. Potapov, O. P. Ivanov, V. E. Stepanov, and L. J. Meng, “Environmental Monitoring Using Large-volume CsI(Tl) Scintillation Counters”, IEEE NSS/MIC Conference Record, 2001.

2000

  • • L. J. Meng, D. Ramsden, “A practical application of gamma-ray spectroscopy in materials analysis”, IEEE NSS/MIC Conference Record, 2000.

1999

  • • M. Dallimore, D. J. Herbert, L.J. Meng, C. P. Datema, D. Ramsden, “Investigation of a Pre-operative Lymph Node Imager using an M-HPD”, IEEE NSS/MIC Conference Record, 1999.
  • • D. J. Herbert, L. J. Meng, D. Ramsden, “A PET detector using Wavelength-shifting fibres”, IEEE NSS/MIC Conference Record, 1999.
  • • L. J. Meng, D.I. Gray, W. B. Gilboy, D. Ramsden and R. Keyser, “Analysis of Building Materials via Their Natural Radioactivity”, IRRMA Conference Proceedings, 1999.
  • • L. J. Meng, D. Ramsden, “Performance result of a DOI encoding PET detector”, IEEE NSS/MIC Conference Record, 1999.
  • • L. J. Meng, D. Ramsden, “Inter-comparison of three algorithms for gamma-ray spectrum deconvolution”, IEEE NSS/MIC Conference Record, 1999.